将某些细菌及病毒特有的药物敏感基因转导入肿瘤细胞 ,从而达到治疗肿瘤的目的 ,称为肿瘤的自杀基因治疗。自杀基因疗法因其独有的旁观者效应 ,可克服基因转导率低的缺陷 ,又可以和放疗、免疫基因治疗联合应用 ,是较为有效并具有临床应用前景的基因疗法。 Transmitting certain bacterial and virus-specific drug-sensitive genes into tumor cells to achieve the purpose of treating tumors, called suicide gene therapy for tumors. Due to its unique bystander effect, suicide gene therapy can overcome the defect of low gene transduction rate, and can be combined with radiotherapy and immune gene therapy. It is a more effective gene therapy with clinical application prospects.