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直肠肛门畸形为先天性畸形中较常见的一种,活婴发病率约1/5000。当合并其他先天性畸形如脊髓、椎管及泌尿生殖系统畸形时,常被称为尾部退化综合征,该综合征由Duham el于1961年首先报道,并定义为骨骼、泌尿生殖系及直肠肛门系贯性畸形,一方面表现为无足并腿畸胎,另一方面为肛门
Anorectal anomalies are the more common forms of congenital malformations and the incidence of living infants is about 1/5000. When combined with other congenital anomalies such as spinal cord, spinal canal and genitourinary system deformity, often referred to as tail degeneration syndrome, the syndrome was first reported by Duham el in 1961 and is defined as skeletal, genitourinary and rectal anus Consistency deformity, on the one hand showed no leg and teratogenic, on the other hand, anus