本文报道一例慢性粒细胞白血病长期存活者,在用马利蓝治疗时导致一过性骨髓抑制后出现大量类高雪细胞,可能与严重的造血紊乱有关.车某某,女、43岁,患慢性粒细胞白血病10年,曾多次用马利蓝治疗.因发热、出血及骨痛半个月于1987年9月入院,Hb:94.5g/L,WBC:96.6×10~9/L,可见幼粒细胞,血小板23×10~9/L.骨髓增生明显活跃,粒系0.89,以中晚幼、杆状核细胞为主.给予马利蓝治疗(每日6mg),第21天出现上消化道出血.Hb:37g/L,WBC:3.5×10~9/L,血 This article reports a case of chronic myeloid leukemia long-term survivors, in the treatment of patients with Marital Blue after a transient bone marrow suppression occurred in a large number of high-type snow cells may be related to severe hematopoietic disorders. Chronic myeloid leukemia for 10 years, has been repeatedly treated with Mali blue due to fever, bleeding and bone pain for half a month in September 1987 admission, Hb: 94.5g / L, WBC: 96.6 × 10 ~ 9 / L, Visible promyelocytic, platelet 23 × 10 ~ 9 / L. Significantly active bone marrow proliferation, grain 0.89 to young and middle-aged, rod-shaped nuclei. Male blue treatment (daily 6mg), the first 21 days of emergence Upper gastrointestinal bleeding .Hb: 37g / L, WBC: 3.5 × 10 ~ 9 / L, blood