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目的:研究氧化亚氮吸入镇静对牙科畏惧症儿童患者的临床治疗效果,探讨氧化亚氮的应用浓度。方法:2012年5月至2014年5月,选择来我院口腔科就诊的124例牙科畏惧症儿童患者,观察记录手术时患儿镇静显效所需氧化亚氮的最低浓度和最大耐受浓度,比较应用氧化亚氮前后患儿的心率、氧饱和度的变化,同时采用Houpt行为量表评价氧化亚氮镇静显效浓度。结果:牙科畏惧症儿童患者镇静显效时所需氧化亚氮的最低浓度为22%-67%(48.56%±11.84%),最大耐受浓度为36%-70%(57.22%±10.05%)。患儿吸入氧化亚氮前与吸入后产生手脚麻木感时,心率分别为(88.76±15.63)次/min与(83.34±11.71)次/min,差异有统计学意义(P<0.01)。吸入氧化亚氮前、后,Houpt行为量表评分结果分别为(1.23±0.58)与(4.41±1.20),差异有统计学意义(P<0.01)。结论:最低浓度为22%-67%的氧化亚氮用于牙科畏惧症儿童患者是安全有效的。
Objective: To study the clinical effect of nitrous oxide inhalation sedation on dental fear children and explore the application concentration of nitrous oxide. METHODS: From May 2012 to May 2014, 124 dental dialectic children who were selected for dental treatment in our department were enrolled in this study. The lowest concentration of nitrous oxide and the highest concentration of nitrous oxide required for the sedation were recorded. The changes of heart rate and oxygen saturation of children before and after nitrous oxide were compared, and the Houpt behavior scale was used to evaluate the effective concentration of nitrous oxide. Results: The minimum required concentration of nitrous oxide for children with dental fear onset was 22% -67% (48.56% ± 11.84%) and the maximum tolerated concentration was 36% -70% (57.22% ± 10.05%). The heart rate was (88.76 ± 15.63) beats / min and (83.34 ± 11.71) beats / min, respectively, before and after inhalation of nitrous oxide. The difference was statistically significant (P <0.01). Before and after inhalation of nitrous oxide, the Houpt behavior scale score was (1.23 ± 0.58) and (4.41 ± 1.20) respectively, with significant difference (P <0.01). Conclusion: Nitrous oxide with a minimum concentration of 22% -67% is safe and effective for children with dental phobia.