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目的讨论应用氯沙坦治疗原发性高血压合并左室肥厚患者的疗效。方法选择我院2011年4月——2012年8月间,患有原发性高血压并伴随左室增厚的患者52例,随机分为观察组和对照组各26例,对照组用常规基础治疗,观察组在此基础上用氯沙坦治疗,治疗3个月后,比较两组患者的疗效。结果观察组总有效率为84.6%,对照组总有效率为61.5%,两组差异显著,p<0.05,具有统计学意义。观察组患者左室增厚逆转,各项指标有明显改善,与对照组相比,p<0.05,具有统计学意义。结论原发性高血压伴随左室肥厚的患者,在基础治疗中加入氯沙坦,可以改善症状,使左室增厚得到逆转,疗效显著,值得信赖。
Objective To discuss the effect of losartan on patients with essential hypertension and left ventricular hypertrophy. Methods From April 2011 to August 2012, 52 patients with essential hypertension and left ventricular hypertrophy were randomly divided into observation group (26 cases) and control group (26 cases), and control group The basic treatment, the observation group on the basis of losartan treatment, three months after treatment, the efficacy of the two groups were compared. Results The total effective rate was 84.6% in the observation group and 61.5% in the control group, with significant difference between the two groups (p <0.05). In the observation group, the left ventricular thickening was reversed and the indexes were significantly improved. Compared with the control group, p <0.05 was statistically significant. Conclusion In patients with essential hypertension with left ventricular hypertrophy, adding losartan to the basic treatment can improve the symptoms and reverse the left ventricular thickening. The curative effect is remarkable and reliable.