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目的对比分析液基细胞学与组织病理学对CIN诊断的符合率,进一步探讨二者对宫颈病变的诊断价值。方法选择1548例在我院宫颈门诊就诊、经液基细胞学检查结果异常,行阴道镜下多点活检患者的临床及病理资料进行回顾性分析。结果 TCT显示:ASC+AGC676例(50.1%);ASCH112例(7.2%);LSL474例(30.6%);HSL186例(12.0%)。宫颈活检为慢性宫颈炎(37.3%),CINⅠ602例(38.8%),CINⅡ200例(12.9%),CINⅢ(含原位癌)154例(9.9%,重度不典型增生140例,原位癌14例),宫颈浸润癌14例(0.9%)。细胞学显示高度上皮内病变高发年龄组为30～39岁,宫颈活检显示高级别病变高发年龄组亦为30～39岁,二者相同。结论液基细胞学与宫颈组织病理学诊断有较高的符合率,二者结合能大大提高对高级别宫颈上皮内瘤变及宫颈癌的早期检出率,减少漏诊的发生。
Objective To compare and analyze the coincidence rates of liquid-based cytology and histopathology in the diagnosis of cervical intraepithelial neoplasia (CIN), and to further explore the diagnostic value of the two in the diagnosis of cervical lesions. Methods A retrospective analysis was made on the clinical and pathological data of 1548 cases treated by cervical biopsy in our hospital and abnormal liquid liquid cytology. Results TCT showed: ASC + AGC676 cases (50.1%); ASCH112 cases (7.2%); LSL474 cases (30.6%); HSL186 cases (12.0%). Cervical biopsy was chronic cervicitis (37.3%), CINⅠ602 cases (38.8%), CINⅡ200 cases (12.9%), CINⅢ (including carcinoma in situ) 154 cases (9.9%, severe dysplasia 140 cases, 14 cases of carcinoma in situ ), Invasive cervical cancer in 14 cases (0.9%). Cytology showed a high incidence of intraepithelial lesions in the age group of 30 to 39 years old, cervical biopsy showed that high-grade lesions in the age group is also 30 to 39 years old, both the same. Conclusion Liquid-based cytology and cervical histopathology have a high coincidence rate, the combination of the two can greatly improve the high-grade cervical intraepithelial neoplasia and cervical cancer early detection rate and reduce the occurrence of missed diagnosis.