生长因子包括成纤维细胞生长因子参与创伤组织修复的调控理论已趋成熟,并已成功地应用到临床前期研究,取得令人鼓舞的效果[1]。根据此论据,我科于1996年3月开始对门诊就诊的外伤性鼓膜穿孔病人26人及慢性化脓性中耳炎静止期3人(4耳)行bFGF局部滴耳治疗,其疗效显著,有效率93.3%, The regulatory theory of growth factors, including the involvement of fibroblast growth factor in the repair of wound tissue, has matured and has been successfully applied to preclinical studies with promising results [1]. According to this argument, we started 26 cases of traumatic tympanic membrane perforation and 3 cases (4 ears) of chronic suppurative otitis media with local ear drop ear treatment in clinic in March 1996, and the curative effect is remarkable, the effective rate is 93.3 %,