目的 :提高医院临时处方溃结Ⅰ号保留灌肠剂的稳定性 ,并对其中的主要成分含量进行控制。方法 :制备时加入助悬剂 ,用沉降容积比和再分散性选择适宜的助悬剂及其最佳助悬浓度 ,并用紫外分光光度法对主要成分柳氮磺吡啶的含量进行测定。结果 :在制剂中加入卡波母作为助悬剂 0 .15 %就可以达到良好的助悬效果 ,而且制备的制剂再分散性好。结论 :加入卡波母作为助悬剂制备的制剂稳定 ,再分散性好 ,便于使用和保存。 OBJECTIVE: To improve the stability of the retention enema I in the temporary prescription of the hospital and to control the content of the main components therein. Methods: The suspending agent was added during the preparation. The suitable suspending agent and its optimum suspending concentration were selected by sedimentation volume ratio and redispersibility. The content of sulfasalazine, the main component, was determined by UV spectrophotometry. Results: Adding Caberborm as a suspending agent at the dosage of 0.15% can achieve good suspending effect, and the preparation prepared has good redispersibility. Conclusion: The preparation of Carbohydrate as a suspending agent is stable, redispersible and easy to use and preserve.