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血管内皮产生的一氧化氮(NO)是一种强有力的血管扩张剂,在稳定血压方面起重要作用。本研究测定肝硬化患者血清中NO的转化物亚硝酸盐及硝酸盐(NO_2~-/NO_3~-)值,以了解其与血浆内毒素水平的关系,还观察肝硬化患者服用多粘菌素E后上述指标的变化,以此探讨肝硬化患者血压偏低的原因。 病人及方法:分四组检测,第一组10例健康对照组,第二组22例代偿期肝硬化,第三组18例肝硬化伴腹水,第四组11例肝硬化伴腹水及功能性肾衰。第二
Nitric oxide (NO) produced by the vascular endothelium is a potent vasodilator that plays an important role in stabilizing blood pressure. This study measured serum nitric oxide and nitrite (NO_2 ~ - / NO_3 ~ -) values in patients with cirrhosis to understand its relationship with plasma endotoxin levels, but also observed in patients with cirrhosis polymyxin E after the above indicators of change, in order to explore the reasons for low blood pressure in patients with cirrhosis. Patients and Methods: Four groups were tested, the first group of 10 healthy controls, the second group of 22 patients with decompensated cirrhosis, the third group of 18 patients with cirrhosis and ascites, the fourth group of 11 patients with cirrhosis and ascites and function Sexual renal failure. second