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作者对细菌感染性疾病患者220人(男94,女126,平均年龄34±SD14yr),其中82例肌肉注射小诺米星(小诺霉素micronomicin,MCR);74例静脉滴注MCR,成人剂量均为120-180mg/d;儿童为3-4mg/(kg·d),疗程5-14d。其余64例肌注庆大霉素(GM)作为对照组。3组的显效率分别为85％,88％,86％,无显著差异。MCR耳毒性甚小而体外抑菌试验证明对革兰阴性菌敏感率(83％)显著地高于GM(69％)是其优点。
The author of 220 patients with bacterial infections (male 94, female 126, mean age 34 ± SD14yr), of which 82 cases of intramuscular injection of small nimotonin (micronizedin microrinin, MCR); 74 cases of intravenous infusion of MCR, adult The dosage was 120-180mg / d; children 3-4mg / (kg · d), treatment 5-14d. The remaining 64 cases were injected gentamicin (GM) as the control group. Significant efficiency of the three groups were 85%, 88%, 86%, no significant difference. MCR ototoxicity is very small and in vitro bacteriostatic test proved its sensitivity to gram-negative bacteria (83%) significantly higher than GM (69%) is its advantage.