我们以强的松、强力宁(potenlin)、环磷酰胺(CTX)联合治疗难治性肾病综合征14例,疗效满意,现报告如下。 临床资料 男6例,女8例,年龄14～56岁,均表现为大量蛋白尿(3.5～6.8g/24h),低白蛋白血症(18～31g/L),高度浮肿(其中6例并发胸腔或腹腔积液)。肾功能正常,在排除继发性肾病综合征后确诊为原发性肾病综合征Ⅱ型,4例曾做肾活检,其中2例为膜性肾病,2例为系膜增生性肾炎。全部14例均经强的松 We use prednisone, potenlin, and cyclophosphamide (CTX) combined treatment of refractory nephrotic syndrome in 14 cases, the results are satisfactory, are as follows. Clinical data of 6 males and 8 females, aged 14 to 56 years old, showed massive proteinuria (3.5 ~ 6.8g / 24h), hypoalbuminemia (18 ~ 31g / L), high edema Complicated by pleural or ascites). Renal function was normal. Nephrotic syndrome type II was diagnosed after secondary nephrotic syndrome was excluded. Four patients had renal biopsy, of which 2 were membranous nephropathy and 2 were mesangial proliferative glomerulonephritis. All 14 cases were prednisone