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目的了解枸杞多糖(LBP)在脑胶质瘤患者术后放疗和化疗中的效果和患者抗肿瘤的作用。方法对照组术后2周始行肿瘤的放疗,疗程6周,再化疗4疗程,对行放疗和化疗的患者常规保肝,对不良反应对症处理。试验组(26例)在同样的条件下增加LBP的服用,浓度为100μg/ml,8 mg/(kg.d)。观察2组患者的效果。结果服用LBS患者放疗和化疗后出现不良反应患者例数少于对照组;不良反应出现的时间、程度和耐受性与对照组比较,差异均有统计学意义(P<0.05)。结论 LBP能显著减轻脑胶质瘤患者的不良反应,降低复发率,增强机体抗肿瘤的功能。
Objective To understand the effect of lycium barbarum polysaccharide (LBP) in postoperative radiotherapy and chemotherapy in patients with glioma and its anti-tumor effect. Methods The control group received radiotherapy for 2 weeks after operation. The course of treatment was 6 weeks, followed by 4 cycles of chemotherapy. Conventional radiotherapy and chemotherapy were given to patients with hepatotoxicity and symptomatic treatment of adverse reactions. The test group (n = 26) was given LBP at the same conditions at concentrations of 100 μg / ml and 8 mg / (kg.d). The effect of two groups of patients was observed. Results The number of adverse reactions in patients with LBS after radiotherapy and chemotherapy was less than that in the control group. The time, degree and tolerability of adverse reactions were significantly different from those in the control group (P <0.05). Conclusion LBP can significantly reduce the adverse reactions in patients with glioma, reduce the recurrence rate and enhance the body’s anti-tumor function.