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外伤性前房出血治疗的关键之一是预防继发性出血、减少并发症的发生。氨基己酸是一种有效的抗纤维蛋白溶解药物,能延迟受损血管中血栓的溶解和脱落。大量临床双盲对照及动物实验研究均表明,该药能明显地降低继发性前房出血的发生率,是目前临床上预防继发性前房出血疗效最为肯定的药物,值得临床推广。本文就该药预防继发性前房出血的机理、用药方法与剂量、副作用及其处理等进行了综述。
One of the keys to the treatment of traumatic hyphema is to prevent secondary bleeding and reduce the incidence of complications. Aminocaproic acid is a potent anti-fibrinolytic drug that delays the dissolution and shedding of blood clots in damaged blood vessels. A large number of clinical double-blind control and animal studies have shown that the drug can significantly reduce the incidence of secondary hyphema is the most effective clinical prevention of secondary hypophaealgia drug efficacy, worthy of clinical promotion. This article reviews the mechanism of drug prevention of secondary hyphema, drug use and dosage, side effects and treatment.