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用盐酸博安霉素（ＢｏａｎｍｙｃｉｎＨｙｄｒｏｃｈｌｏｒｉｄｅ，ＢＡＭ）对８０例恶性肿瘤进行了Ⅱ期临床研究，单药治疗１５例，可评价疗效１３例，有效率７／１３（５３．８％）。其中舌癌３／４，下咽癌２／２，鼻腔癌１／１，口颊癌１／１。联合化疗６５例，可评价疗效６３例，总有效率３９／６３（６１．９％），其中恶性淋巴瘤１９／２０，肺癌９／１５，肝癌５／１７，鼻咽癌３／６，乳腺癌１／１，其它癌２／３，其主要毒性为发热或伴有轻度寒战，个别病人有皮疹
Eighty cases of malignant tumors were studied in phase Ⅱ with Boanmycin Hydrochloride (BAM). Fifteen patients were treated with monotherapy. Thirteen cases were evaluated and the response rate was 7/13 (53.8%). Among them, tongue cancer 3/4, hypopharyngeal cancer 2/2, nasal cancer 1/1, mouth cheek cancer 1/1. The combination of chemotherapy in 65 cases, the evaluation of curative effect in 63 cases, the total effective rate 39/63 (61.9%), of which 19/20 malignant lymphoma, lung cancer 9/15, liver cancer 5/17, nasopharyngeal cancer 3/6, breast Cancer 1/1, other cancers 2/3, the main toxicity is fever or mild chills, individual patients have a rash