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目的 探讨小儿生活活动强度指数、脂联素和瘦素、胰岛素、血糖、脂质等生活习惯疾病相关因子的关系。方法 于 2 0 0 2年 7月测定 81名儿童血清脂联素、瘦素、胰岛素、血糖、甘油三酯 (TG)、胆固醇 (TC)、高密度脂蛋白胆固醇 (HDL C)、低密度脂蛋白胆固醇 (LDL C)、载脂蛋白A(ApoA)、载脂蛋白B(ApoB)等指标。并进行了 1周的生活活动时间和营养状况的调查 ,计算出每日的生活活动强度指数和所摄入的热量。结果 日强度指数和HDL C、ApoA呈正相关 (r =0 2 2 9,P <0 0 5 ;r =0 2 75 ,P <0 0 5 )。脂联素和体重指数 (BMI)、体脂肪率 (脂肪组织占体重百分比 )呈负相关。不同性别之间脂联素、热量、脂质差异有显著性意义 (P <0 0 1,P <0 0 5 ,P <0 0 5 )。结论 在儿童时期开始提高生活活动强度指数 ,促进能量消费 ,能提高HDL C、脂联素 ,降低BMI和体脂肪率 ,从而降低未来发生肥胖症、糖尿病、动脉硬化等生活习惯疾病的可能性。血清脂联素浓度在儿童女性高于男性。
Objective To investigate the relationship between activity index of life activity, related factors of adiponectin and lifestyle-related diseases such as leptin, insulin, blood glucose and lipid. Methods Serum adiponectin, leptin, insulin, blood glucose, triglyceride (TG), cholesterol (TC), high density lipoprotein cholesterol (HDL C), low density lipoprotein (LDL C), apolipoprotein A (ApoA), apolipoprotein B (ApoB) and other indicators. And conducted a week of life activities and nutritional status of the survey to calculate daily life activity index and intake of calories. Results The daily intensity index was positively correlated with HDL C, ApoA (r = 0 2 2 9, P <0 05; r = 0 2 75, P 0 05). Adiponectin and body mass index (BMI), body fat percentage (adipose tissue as a percentage of body weight) was negatively correlated. There were significant differences in adiponectin, calories and lipid among different genders (P <0.01, P <0.05, P <0.05). CONCLUSIONS: It is possible to increase HDL C, adiponectin, lower BMI and body fat percentage in childhood so as to reduce the intensity of life activity index, reduce the risk of obesity, diabetes, arteriosclerosis and other lifestyle-related diseases in the future. Serum adiponectin concentrations were higher in children than in men.