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目的探讨急性四氯化硅(SiCl4)中毒对机体外周血象的影响,为急性刺激性气体中毒的救治提供依据。方法对119例(131人次)急性四氯化硅中毒患者的血象结果进行回顾性分析。结果急性四氯化硅中毒除可引起明显的局部刺激症状和全身中毒反应外,对患者外周血象有明显的影响,中毒早期白细胞升高达43.51%(57/131)例,并呈中性粒细胞百分比升高,淋巴细胞百分比下降的“粒淋分离”现象。嗣后白细胞逐渐下降,淋巴细胞逐渐上升,一周后基本恢复正常。嗜酸性粒细胞、嗜碱性粒细胞及单核细胞数量及百分比无显著变化。结论急性四氯化硅中毒属于中等溶解度,高浓度,强刺激性气体中毒。可引起病人外周血象明显变化,对其中毒要引起高度重视。
Objective To investigate the effect of acute SiCl4 poisoning on the peripheral blood of the organism and provide basis for the treatment of acute irritant gas poisoning. Methods A retrospective analysis was performed on the blood results of 119 patients (131 persons) with acute poisoning of silicon tetrachloride. Results Acute poisoning of silicon tetrachloride not only caused obvious local irritation and systemic poisoning, but also had obvious effect on the peripheral blood of patients. In the early stage of poisoning, the number of leucocytes increased by 43.51% (57/131) and showed neutrophil Percentage increase, the percentage of lymphocytes decreased “Particle wash separation ” phenomenon. Subsequently, the white blood cells gradually decreased, lymphocytes gradually increased, returned to normal one week later. There was no significant change in the number and percentage of eosinophils, basophils and monocytes. Conclusion Acute toxicity of silicon tetrachloride is medium solubility, high concentration, strong irritant gas poisoning. Can cause significant changes in peripheral blood of patients, its poisoning should be given high priority.