甘柴合剂对急性实验性肝损伤有明显的护肝作用,且为急性病毒性肝炎的临床观察所证实。在此基础上,我们进一步观察了甘柴合剂对动物慢牲肝损伤的影响,发现具有抑制脂肪肝发生、纤维增生的作用。但在临床实践过程中发现有些患者服用甘柴合剂后有浮肿等副作用,为此,我们又在动物实验基础上加进茯苓一味,事实 Ganchai combination has obvious liver protection effect on acute experimental liver injury, and is confirmed by clinical observation of acute viral hepatitis. On this basis, we further observed the effects of Ganchai mixture on animal liver injury and found that it has the effect of inhibiting fatty liver and fibrogenesis. However, during the course of clinical practice, some patients had edema and other side effects after taking Ganchai Mixture. For this reason, we added the blindness to animal experiments.