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目的 了解慢性阻塞性肺病 (COPD)的危险因素 ,为该病的深入研究提供参考。方法 使用成组病例对照研究 ,计算各因素的比值比 (OR)和 95 %的可信区间 (CI) ,并用非条件Logistic回归模型进行多因素逐步回归分析。结果 单因素分析中 ,开始吸烟年限、过敏性疾病、卧室油烟污染、儿童期慢性呼吸系统疾病、对物质过敏、职业危害等因素进入回归模型 ,OR值分别为 4 .6 7、3.5 0、1.4 2、12 .0 0、3.38、2 .78(P <0 .0 5 )。结论 上述因素可能是COPD发病的危险因素 ,有待进一步研究
Objective To understand the risk factors of chronic obstructive pulmonary disease (COPD) and provide reference for the further study of the disease. Methods A case-control study was conducted to calculate the odds ratio (OR) and the 95% confidence interval (CI) of each factor. Multivariate stepwise regression analysis was performed using a non-conditional logistic regression model. Results In the univariate analysis, factors such as years of smoking, allergic diseases, fumes from bedroom, childhood chronic respiratory diseases, substance allergies, occupational hazards and other factors entered the regression model with OR values of 4.676, 3.510, 1.4 2,12 .0 0,3.38,2. 78 (P <0. 05). Conclusion The above factors may be risk factors for the pathogenesis of COPD, pending further study