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炎性作用在心血管疾病中的作用越来越重要,尤其是炎性标记物与冠心病之间的相互作用及关系,近年来被广泛研究,大多研究结果呈现一致性。中性粒细胞与淋巴细胞比值是近些年新兴的炎症标记物,其简易、普及、易获取的特点受到了广泛学者的肯定。NLR与动脉粥样硬化相关,相关研究显示动脉僵硬度、钙化积分与NLR密切相关,另外,高NLR者更易发现易损斑块。NLR可预测急性冠脉综合征的短期及长期心血管事件发生率及死亡率,以及预测稳定性心绞痛预后情况及侧支循环是否丰富。在冠脉造影的应用中,发现NLR不仅与冠脉病变严重程度密切相关,能预测完全闭塞病变的发生,及预测无复流的发生。在已有心血管危险因素的基础上,NLR可作为新成员,为冠心病的发现及其预后的风险评价提供依据。
The role of inflammatory action in cardiovascular diseases is more and more important. In particular, the interaction and relationship between inflammatory markers and coronary heart disease have been extensively studied in recent years, and most of the results are consistent. Neutrophil to lymphocyte ratio is a new inflammatory marker in recent years, its simple, universal, easy to get features has been recognized by a wide range of scholars. NLR and atherosclerosis related studies have shown arterial stiffness, calcification score and NLR are closely related, in addition, high NLR were more vulnerable to the discovery of vulnerable plaque. NLR predicts short-term and long-term cardiovascular events and mortality in patients with acute coronary syndromes and predicts the prognosis of stable angina and whether collateral circulation is abundant. In the application of coronary angiography, we found that NLR is not only closely related to the severity of coronary lesions, can predict the occlusion of the occlusion, and predict the occurrence of no-reflow. Based on the existing cardiovascular risk factors, NLR can serve as a new member to provide evidence for the detection of coronary heart disease and the risk assessment of its prognosis.