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【目的】观察颈丛阻滞复合全麻在颈动脉内膜剥脱术（carotid endarterectomy ，CEA ）中的应用。【方法】将2012年1月至2013年8月在本院行CEA术的40例患者按照麻醉方式分为两组：对照组（G组）20例采用单纯全麻，观察组（GL组）20例采用颈丛复合全麻。观察并分析两组患者围术期的血流动力学变化、苏醒时间以及镇痛药物用量等。采用简易精神状态检查量表（MMSE）观察患者术前1 d、术后1 d、3 d、6 d变化，初步评估患者神经功能。【方法】G L组患者在各时点血流动力学的波动均明显小于G组（ P ＜0．05），术中血管活性药物的使用亦明显低于G组（ P ＜0．05）；G组苏醒时间、镇痛药用量显著多于GL 组（ P ＜0．05）。与术前基础值比较，两组患者术后1 d的MMSE值均明显降低（ P ＜0．05），且G组MMSE值较GL组低，差异有统计学意义（ P ＜0．05）。术后3 d和术后6 d两组的MMSE值与术前基础值相比较均无统计学意义（ P ＞0．05）。【结论】颈丛阻滞复合全麻在颈动脉内膜剥脱术中患者血流动力学稳定，苏醒时间短，镇痛药用量少，术后对神经功能影响小，临床效果满意，能明显提高麻醉安全和质量。“,”[Objective]To observe the application of cervical plexus block combined with general anesthesia in carotid endarterectomy .[Methods] According to anesthesia method ,40 patients undergoing carotid endar-terectomy in our hospital from Jan .2012 to Aug .2013 were randomly divided into control group(G group ,n=20) undergoing general anesthesia group and observation group (GL group ,n = 20) undergoing cervical plexus block combined with general anesthesia .Hemodynamics ,awakening time and the dose of analgesics in two groups were observed and analyzed .Mini-mental state examination(MMSE) was used to observe cognitive function 1d before and 1d ,3d and 6d after operation .[Results] The fluctuation of hemodynamics in GL group at each time point was obviously lower than that in G group ( P<0 .05) ,and the dose of intraoperative vasoac-tive agents was also lower than that in G group( P<0 .05) .The awakening time and the dose of analgesics in G group were markedly more than those in GL group( P<0 .05) .Compared with baseline value before opera-tion ,MMSE score at 1d after operation in two groups was obviously decreased( P<0 .05) ,and MMSE score in G group was lower than that in GL group ,and there was significant difference( P 0 .05) .[Conclusion] Patients undergoing carotid endarterectomy under cervical plexus block com-bined with general anesthesia have stable hemodynamics , short awakening time , little dose of analgesics group ,small impact on neurological function after operation and satisfactory efficacy ,and can obviously im-prove the safety and quality of anesthesia .