目的:探究精选中药小复方对急性心肌缺血大鼠血管内皮细胞的影响。方法:将大鼠随机分为正常组、模型组、阳性对照组、中药低、中、高剂量组,采用Iso(5mg/kg)复制急性心肌缺血大鼠模型,检测各组大鼠造模后血清中NO及ET含量的改变。结果:急性心肌缺血大鼠血清中NO含量均明显降低,ET含量均明显升高。结论:精选中药小复方对急性心肌缺血具有一定的防治和保护作用。 Objective: To explore the effect of selected traditional Chinese medicine Xiaofu Recipe on vascular endothelial cells in acute myocardial ischemia rats. Methods: The rats were randomly divided into normal group, model group, positive control group, traditional Chinese medicine low, medium and high dose groups, the rat model of acute myocardial ischemia was induced by Iso (5mg / kg) After the changes of serum NO and ET content. Results: The levels of NO in serum of acute myocardial ischemia rats were significantly decreased, and the contents of ET were significantly increased. Conclusion: The selected traditional Chinese medicine compound prescription has some preventive and protective effects on acute myocardial ischemia.