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目的评估根不同疗程的标准三联疗法(雷贝拉唑+克拉霉素+阿莫西林)根除幽门螺旋杆菌(Hp)的疗效。方法264例Hp感染的患者随机分为两组，A组：雷贝拉唑(20mg,bid)+克拉霉素(0.5g,bid)+阿莫西林(1g,bid)，疗程7d；B组：雷贝拉唑(20mg,bid)+克拉霉素(0.5g,bid)+阿莫西林(1g,bid)，疗程14d；治疗结束后4~6w复查14C尿素呼气试验评估根除疗效。结果248例按方案完成治疗，A组Hp的根除率71.3.0%，B组Hp的根除率88.9.0%，两组比较差异有统计学意义(<0.05)。结论标准三联疗法适当延长疗程能更有效的根除Hp。“,”Objective To evaluate the root course of dif erent standard triple therapy(rabeprazole azole+clarithromycin+amoxicil in)eradication of helicobacter pylori(Hp)curative ef ect.Methods 264 patients with Hp infection of the patients were randomly divided into two groups:group A:rabeprazole azole(20 mg,the bid)+clarithromycin(0.5 g,the bid)+amoxicil in(1 g,bid),course of 7 d;Group B:rabeprazole azole(20 mg,the bid)+clarithromycin(0.5 g,the bid)+amoxicil in(1 g,bid),period of treatment 14 d;4~6 weeks after treatment to review 14 c urea breath test to evaluate the eradication of curative ef ect.Results 248 cases of complete treatment according to the plan,A set of Hp eradicate rate 71.3.0%,Hp eradicate rate 88.9.0%,group B is similar between the two groups have statistical significance ( <0.05).Conclusion The standard triple therapy extend treatment can be more ef ective if Hp eradication.