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目的分析乳腺癌术后出现内乳淋巴结(IMLN)转移16例的预后。方法乳腺癌术后IMLN转移患者16例,10例行序贯化放疗,4例行化疗,2例行内分泌治疗。回顾性分析患者的临床特点及预后。结果随访3~77个月,随访期死亡12例,生存4例。16例患者中位生存期29.5个月,1、2和3年总生存率分别为87.5%、56.3%和41.7%。11例多发转移患者中位生存期20.0个月,1、2和3年生存率分别为81.8%、36.4%和18.2%。5例单发转移患者中,1例死亡,4例随访期无疾病进展。IMLN单发转移者预后较好。结论乳腺癌术后随访应重视IMLN状况;单发IMLN转移患者早发现、早治疗仍可获得较好预后。
Objective To analyze the prognosis of 16 cases of internal mammary lymph node metastasis (IMLN) after operation of breast cancer. Methods Sixteen patients with IMLN metastasis after breast cancer surgery were treated with sequential chemoradiotherapy (10 cases), chemotherapy (4 cases) and endocrine therapy (2 cases). Retrospective analysis of the clinical features and prognosis of patients. The results were followed up for 3 to 77 months, 12 cases died during the follow-up period, and 4 cases survived. The median survival time was 29.5 months in 16 patients and 87.5%, 56.3% and 41.7% respectively in 1, 2 and 3 years. The median survival of 11 patients with multiple metastases was 20.0 months, and the 1, 2, and 3-year survival rates were 81.8%, 36.4%, and 18.2%, respectively. Of 5 patients with single metastasis, 1 died and 4 patients had no disease progression at follow-up. IMLN single metastasis better prognosis. Conclusion The postoperative follow-up of breast cancer should pay attention to the status of IMLN. The patients with single IMLN metastasis may have good prognosis after early detection and early treatment.