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近来的资料表明,快中子治疗对某些肿瘤病人有肯定的优点,本文讨论快中子治疗的指征及评价。 唾液腺肿瘤:由于肿瘤位于浅表,低能量的中子束效果也佳。据三篇报道,肿瘤的持久局部控制分别可达75％、73％、81％。疗效与手术加常规放疗相似,但中子治疗的肿瘤病人较大(41×40mm~2～126×115mm~2)。三年存活率分别为54％,20％,60％。差异颇大,因三组病例病理类型不同。局限性,病灶大而不能手术的,分化好的唾液腺肿瘤较适合快中子治疗。 头颈部肿瘤:每周两次快中子照射加三次常规照射的效果比单纯中子一周两次的疗效好。局部控制率依次为45％及47％,并发症依次为零及18％。手术,
Recent data indicate that fast neutron therapy has certain advantages for certain cancer patients. This article discusses the indications and evaluation of fast neutron therapy. Salivary gland tumors: Because the tumors are superficial, low-energy neutron beams are also effective. According to three reports, the persistent local control of tumors can reach 75%, 73%, and 81%, respectively. The curative effect is similar to that of surgery plus conventional radiotherapy, but the tumor patients treated with neutrons are larger (41×40 mm~2~126×115 mm~2). The three-year survival rates were 54%, 20%, and 60%, respectively. The differences are considerable because of the different pathological types of the three groups. Limitations, large lesions and inoperable, well-differentiated salivary gland tumors are more suitable for fast neutron therapy. Head and Neck Cancer: Fast neutron irradiation twice a week plus three times conventional irradiation is more effective than neutrons twice a week. The local control rates were 45% and 47%, respectively, and the complications were zero and 18%. surgery,