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目的探讨脓毒性休克早期液体复苏的临床反应性。方法对2008年2月～2010年2月38例采用早期目标定向治疗方案治疗的脓毒性休克患者按是否存活进行分组,就中心静脉压、心率、平均动脉压、输液量、尿量、血乳酸等指标进行评价。结果 38例采用早期目标定向治疗方案治疗6h均达标,存活21例(55.26%),死亡17例(44.74%),两组患者输液总量及输液种类差异无统计学意义(P>0.05),存活组6、24h尿量及血乳酸清除率明显优于死亡组(P<0.05)。结论血乳酸清除率及尿量可作为脓毒性休克液体复苏有效的临床监测指标。
Objective To investigate the clinical response of early liquid resuscitation in septic shock. Methods From February 2008 to February 2010, 38 patients with septic shock who were treated by early targeted therapy were divided into groups according to whether they survived or not, and the mean arterial pressure, heart rate, mean arterial pressure, infusion volume, urine output, blood lactate And other indicators for evaluation. Results 38 cases were treated with early target-oriented therapy for 6h, and 21 cases (55.26%) survived and 17 (44.74%) died. There was no significant difference in the total amount of infusion and infusion between the two groups (P> 0.05) Survival group 6,24 h urine output and blood lactic acid clearance was significantly better than the death group (P <0.05). Conclusions The blood lactate clearance rate and urine output may be used as effective clinical indicators for the recovery of septic shock fluid.