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目的评价玻璃体切割术联合曲安奈德治疗难治性黄斑水肿的疗效。方法我院2002年2月至2005年9月应用玻璃体切割术治疗难治性黄斑水肿患者42例47眼,根据术中是否行玻璃体腔注射曲安奈德随机分为曲安奈德治疗组和对照组,术后随访(4-7)m,比较两组患者视力改善黄斑水肿消退情况。结果两组患者治疗后视力及黄斑水肿均明显改善,治疗前后有统计学差异,p<0.05。并且曲安奈德治疗组视力改善及黄斑水肿消退情况均明显优于对照组,有统计学差异,p<0.05。结论玻璃体切割术是目前治疗难治性黄斑水肿比较有效的方式,而术中应用曲安奈德将使该治疗效果显著性提高。
Objective To evaluate the efficacy of vitrectomy combined with triamcinolone acetonide in the treatment of refractory macular edema. Methods 42 patients (47 eyes) with refractory macular edema underwent vitrectomy from February 2002 to September 2005 in our hospital were randomly divided into triamcinolone acetonide treatment group and control group according to intravitreous injection of triamcinolone acetonide , Followed up (4-7) m, the visual acuity was compared between the two groups to improve the regression of macular edema. Results The visual acuity and macular edema in both groups were significantly improved after treatment, with statistical difference before and after treatment (p <0.05). And triamcinolone acetonide treatment group visual acuity and macular edema subsided were significantly better than the control group, with statistical differences, p <0.05. Conclusions Vitrectomy is the most effective way to treat refractory macular edema. However, the use of triamcinolone acetonide intraoperatively improves the therapeutic effect significantly.