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作者报道了由用DNA重组方法获得的无毒性百日咳毒素（PT－9K／129G）构成的无细胞菌苗对婴幼儿的安全性和兔疫原性。研究表明PT－9K／129G比化学脱毒的PT分子更安全、更具有兔疫原性。无细胞菌苗应能诱
The authors report on the safety and immunogenicity of a cell-free bacterin, consisting of the avirulent pertussis toxin (PT-9K / 129G) obtained by DNA recombination, in infants and toddlers. Studies have shown that PT-9K / 129G is safer and more virulent than chemically detoxified PT molecules. Acellular vaccine should be able to induce