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目的观察血必净对脑梗死患者血清细胞因子(IL-8、TNF-α、IL-6)炎性细胞因子影响评价脑梗死患者的治疗作用,以期为临床工作提供理论帮助。方法选择在我院住院诊治的100例脑梗死患者,随机分为两组,治疗组共50例在常规治疗基础上加用血必净治疗,对照组共50例常规治疗;两组患者均于治疗前及治疗后留取静脉血,应用酶联免疫吸附实验(ELISA)检测血清中(IL-8、TNF-α、IL-6)的表达,观察血必净对两组患者的疗效及对血清中(IL-8、TNF-α、IL-6)表达的影响。结果治疗组总有效率明显高于对照组,治疗组与对照组治疗后比较(IL-8、TNF-α、IL-6)明显下降。结论血必净能明显降低血清中(IL-8、TNF-α、IL-6)的表达,对脑梗死患者有明显治疗作用。
Objective To observe the effects of Xuebijing on the inflammatory cytokines (IL-8, TNF-α, IL-6) in patients with cerebral infarction in the evaluation of the therapeutic effect of cerebral infarction in order to provide theoretical help for clinical work. Methods Selected 100 patients with cerebral infarction hospitalized in our hospital were randomly divided into two groups, the treatment group of 50 patients on the basis of conventional treatment plus Xuebijing treatment, the control group of 50 cases of conventional treatment; two groups of patients were in Venous blood was collected before and after treatment. Serum levels of IL-8, TNF-α and IL-6 were detected by enzyme-linked immunosorbent assay (ELISA) Serum (IL-8, TNF-α, IL-6) expression. Results The total effective rate in the treatment group was significantly higher than that in the control group. The levels of IL-8, TNF-α and IL-6 in the treatment group and the control group were significantly decreased after treatment. Conclusion Xuebijing can significantly reduce the serum (IL-8, TNF-α, IL-6) expression in patients with cerebral infarction has a significant therapeutic effect.