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目的:研究中国乳腺癌诊断年龄并比较与美国乳腺癌诊断年龄的差异。方法:收集从1975年-2005年间西京医院收治的乳腺癌病例,对诊断年龄分布进行统计分析,并与美国Surveillance Epidemiology End Results(SEER)数据库数据比较。结果:获得乳腺癌患者3074例,诊断年龄范围17-91岁,平均48.65岁;高峰集中在45-54岁年龄段,共1006例,占总患病人数的32.73%;<35岁的年轻型乳腺癌297例,占9.67%。而美国SEER数据显示,2002年-2005年间美国乳腺癌平均诊断年龄为61岁;高峰集中在55-64岁年龄段,占总患病人数的23.7%;<35岁的年轻型乳腺癌占总患病人数1.9%。同期中美乳腺癌平均诊断年龄及总体年龄分布存在显著差异(P<0.01)。结论:我国乳腺癌患者的诊断年龄较美国年轻,与美国SEER公布数据相比,乳腺癌诊断平均年龄和高峰年龄段明显提前,年轻型乳腺癌患者所占比例明显增高。
Objective: To study the age of diagnosis of breast cancer in China and compare it with the age of diagnosis of breast cancer in the United States. METHODS: Breast cancer cases from Xijing Hospital between 1975 and 2005 were collected and statistical analysis was performed on the age distribution of the diagnosis and compared with the Surveillance Epidemiology End Results (SEER) database. RESULTS: A total of 3074 patients with breast cancer were diagnosed. The age range of diagnosis was 17-91 years old, with an average of 48.65 years. The peaks were concentrated in the 45-54 age group with a total of 1006 cases, accounting for 32.73% of the total number of patients; 297 cases of breast cancer, accounting for 9.67%. The US SEER data show that the average diagnosis age of breast cancer in the United States from 2002 to 2005 was 61 years; the peak was concentrated in the 55-64 age group, accounting for 23.7% of the total number of patients; young breast cancer < 35 years of the total The number of patients suffering from 1.9%. The mean age of diagnosis and the overall age distribution of breast cancer in China and the United States during the same period were significantly different (P<0.01). Conclusion: The diagnostic age of breast cancer patients in China is younger than in the United States. Compared with the data published by the US SEER, the average age of diagnosis and peak age of breast cancer are significantly advanced, and the proportion of young breast cancer patients is significantly higher.