目的:为了研究细胞因子在小儿反复呼吸道感染中的作用。方法：本文采用免疫分析技术对反复呼吸道感染患儿血清中ＩＬ－２（白细胞介素- ２）、ＩＬ－８（白细胞介素- ８）、ＳＩＬ－２Ｒ（可溶性ＩＬ－２受体）、ＴＦ－α（肿瘤坏死因子α）、ＴＧＦ－β（转化生长因子-β ）和ＩＣＡＭ－１（细胞间粘附分子- １）等细胞因子水平进行测定。结果：患儿血清中ＩＬ－２，ＳＩＬ－２Ｒ，ＩＬ－８，ＴＮＦ—α及ＩＣＡＭ—ｌ水平均显著高于正常对照（Ｐ＜０．０１）。结论：细胞因子的释放与患儿反复呼吸道感染有关。 Objective: To investigate the role of cytokines in recurrent respiratory tract infections in children. Methods: The serum levels of IL-2, IL-8, IL-2, IL-2 and IL-2 in children with recurrent respiratory tract infection were detected by immunoassay Α (tumor necrosis factor α), TGF-β (transforming growth factor-β) and ICAM-1 (intercellular adhesion molecule-1) were measured. Results: Serum levels of IL-2, SIL-2R, IL-8, TNF-α and ICAM-1 in children were significantly higher than those in normal controls (P <0.01). Conclusion: The release of cytokines is associated with recurrent respiratory tract infections in children.