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目的:探讨脑损伤患者凝血功能水平与颅脑损伤伤情转归的相关性。方法:收集70例颅脑损伤患者的临床资料,伤者抽取静脉血2 mL,进行凝血功能检测,分析结果与临床资料等分别采用SPSS 11.5软件进行χ2检验和logistic回归分析。结果:在13例凝血功能异常患者中有5例(38%)伤情加重(较入院时脑内血肿体积增大,迟发性血肿等),明显高于凝血功能正常而伤情加重者(12%,P<0.05);单因素和多因素logistic回归分析提示凝血功能异常时脑损伤伤情加重的危险因素。结论:脑创伤后凝血功能异常时颅脑损伤患者伤情加重的危险因素。
Objective: To investigate the correlation between coagulation level and the outcome of traumatic brain injury in patients with brain injury. Methods: The clinical data of 70 patients with craniocerebral injury were collected. The venous blood was drawn from 2 mL of the venous blood to detect the coagulation function. The analysis results and clinical data were analyzed by χ2 test and logistic regression respectively. Results: In 13 patients with coagulation abnormalities, 5 patients (38%) were more exacerbated (compared with the increase of intracerebral hematoma volume and delayed hematoma on admission), which was significantly higher than those with normal coagulation function 12%, P <0.05). Univariate and multivariate logistic regression analysis indicated that the risk factors of aggravating injury of brain injury in coagulation dysfunction. Conclusion: The risk factors of exacerbations of traumatic brain injury in patients with abnormal coagulation after traumatic brain injury.