乳腺癌如今已成为威胁女性健康的主要恶性肿瘤,全世界每年有100多万女性罹患乳腺癌,40多万女性死于乳腺癌。分子靶向药物治疗是乳腺癌个体化治疗的又一新的突破,目前的研究进展主要集中在针对Her-2基因(人类表皮生长因子-2),它是由原癌基因编码的Her-2受体,Her-2在调控正常细胞的生长发育和分化中起重要作用。在欧美国 Breast cancer is now a major malignancy that threatens women’s health. More than 1 million women worldwide suffer from breast cancer each year, and more than 400,000 women die from breast cancer. Molecular targeted drug therapy is another breakthrough in the individualized treatment of breast cancer. The current research progress is mainly focused on the Her-2 gene (human epidermal growth factor-2), which is encoded by proto-oncogene Her-2. The receptor, Her-2, plays an important role in regulating the growth and differentiation of normal cells. In the United States