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以往认为,氟化物主要作用于牙齿和骨骼,实际上,氟几乎影响到每一器官(Waldbolt 氏,1976)。肠上皮在对物质的消化和吸收上具有重要作用,故本实验是研究相对急性和低浓度氟化物对大鼠原位肠上皮功能的影响。实验选用体重为200～500g 的雄性大鼠。动物彻夜禁食,任意饮水。每组5只大鼠。乙醚麻醉,沿腹中线切开腹部,通过小肠两切口(一切口在十二指肠—空肠交界点的稍远处;另一切口在回肠末端),用37℃盐水洗涤后,结扎远端开口,通过近端开口,用
In the past, fluoride was mainly applied to the teeth and bones. In fact, fluoride affected almost every organ (Waldbolt, 1976). Intestinal epithelium in the digestion and absorption of substances has an important role, so this experiment is to study the relatively acute and low concentrations of fluoride on rat intestinal function in situ. Experimental selection of male rats weighing 200 ~ 500g. Animal fasting overnight, drinking water. Five rats in each group. Anesthesia was induced by ether. The abdomen was dissected along the midline and passed through two incisions in the small intestine (one incision at a slight distance from the duodenum-jejunum junction and the other incision at the distal end of the ileum). After washing with saline at 37 ° C, the distal opening , Through the proximal opening, with