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INTRODUCTION Helicobacter pylori(Hp)infection has beenconsidered to play significant roles in pathogenesisof peptic ulcer.Additionally Hp is associated withthe development of gastric epithelial hyperplasiaand lymphoid malignancies.The InternationalAgency for Research on Cancer has classified lip asa class Ⅰ carcinogen and a definite cause of gastriccancer in humans.Hp infection first causes chronicactive gastritis and may slowly lead to infection ofwhole stomach.In the late stages of infection,mucosal atrophy and intestinal metaplasia(IM),
INTRODUCTION Helicobacter pylori(Hp) infection has beenconsidered to play significant roles in pathogenesis of peptic ulcer.Additionally Hp is associated with the development of gastric epithelial hyperplasiaand lymphoid malignancies.The International Agency for Research on Cancer has classified lip asa class I carcinogen and a definite cause of gastriccancer In humans.Hp infection first cause chronicactive gastritis and may slowly lead to infection ofwhole stomach.In the late stages of infection,mucosal atrophy and intestinal metaplasia(IM),