论文部分内容阅读
目的评价空芯针穿刺活检(core needle biopsy,CNB)在乳腺肿瘤中的诊断价值。方法回顾性分析2009年1月至2013年10月北京大学第一医院乳腺中心1394例超声引导下CNB的病理资料,并与术后组织病理学检查结果进行比较,评价CNB诊断的价值。结果 1394例病人乳腺病灶组织中CNB病理诊断乳腺癌1037例,术后病理组织学诊断乳腺癌1046例,CNB病理诊断假阴性9例。CNB病理诊断乳腺癌的灵敏度为99.1%。特异度为100%,准确率为99.4%,阳性预测值为100%,阴性预测值为97.5%,约登指数为0.991,Kappa值为0.983(P<0.01)。结论 CNB组织病理诊断乳腺病灶具有较高的准确性,与术后病理组织学诊断结果一致性较高,是一种准确、快速、创伤小的乳腺病灶活检方法。
Objective To evaluate the diagnostic value of core needle biopsy (CNB) in breast tumors. Methods The clinical data of 1394 cases of CNB under ultrasound guidance from January 2009 to October 2013 in Peking University First Hospital Breast Center were retrospectively analyzed and compared with postoperative histopathological findings to evaluate the value of CNB diagnosis. Results A total of 1037 cases of breast cancer with CNB pathological diagnosis were diagnosed in 1394 cases of breast lesions, 1046 cases of postoperative pathological diagnosis of breast cancer and 9 cases of false negative of CNB pathological diagnosis. The sensitivity of CNB pathological diagnosis of breast cancer was 99.1%. The specificity was 100%, the accuracy was 99.4%, the positive predictive value was 100%, the negative predictive value was 97.5%, the Youden index was 0.991, and the Kappa value was 0.983 (P <0.01). Conclusions CNB histopathological diagnosis of breast lesions with high accuracy, and histopathological diagnosis of postoperative consistency is high, is a accurate, rapid, less invasive method of breast lesions biopsy.