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2011年Kim等[1]的研究中描述了使用康斯特(HTK)心脏停搏液后小儿心脏病患者血钠浓度的波动情况。在其研究中回顾了628例小儿患者,其血钠水平下降幅度超过15 mmol/L,从而引起了血钠浓度的显著波动;研究同时指出18例患儿术后癫痫发作与血钠浓度显著减低之间是明显相关的。作者认为给予HTK液后引起严重的低血钠,随之在术后引发神经系统并发症。笔者对此表示怀疑,认为
In 2011, Kim et al. [1] described the fluctuation of serum sodium concentration in children with heart disease after using cardioplegic solution of ketamine (HTK). In her study, 628 pediatric patients were reviewed and their serum sodium levels decreased by more than 15 mmol / L, causing significant fluctuations in serum sodium concentrations. The study also showed that seizures and serum sodium concentrations were significantly reduced in 18 of the 18 children There is a clear correlation between them. The authors believe that given HTK solution caused severe hyponatremia, followed by postoperative neurological complications. I doubt that, I think