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目的探讨不同抗高血压药物对于男性勃起功能的影响。方法问卷调查2008年10月至2008年12月来我院就诊的已婚男性、原发性高血压患者244例,年龄40～70岁。记录服用的抗高血压药物并应用国际勃起功能指数-5(IIEF-5)评估其勃起功能。结果244例高血压患者勃起功能正常者69例(28.28%),勃起功能障碍(ED)者1 75例(71.72%)。其中轻度障碍者1 20例(49.1 8%),中度障碍者16例(6.56%),重度障碍者39例(15.98%)。β受体阻滞剂组IIEF分值低于非β受体阻滞剂组,ED发生率高于非β受体阻滞剂组,其他药物组如血管紧张素转换酶抑制剂组、血管紧张素Ⅱ受体拮抗剂组、钙离子拮抗剂组、利尿剂组间差异均无统计学意义。结论高血压患者中ED的发生率较高(175/244,71.72%),服用β受体阻滞剂对患者勃起功能有不利影响,而其他药物对于勃起功能影响相似。
Objective To investigate the effect of different antihypertensive drugs on male erectile function. Methods A total of 244 married men and women with essential hypertension were enrolled in our hospital from October 2008 to December 2008. The patients were 40-70 years old. The antihypertensive drugs taken were recorded and their erectile function assessed using the International Index of Erectile Function -5 (IIEF-5). Results There were 69 cases (28.28%) with erectile dysfunction in 244 cases of hypertension, and 75 cases (71.72%) with erectile dysfunction (ED). Among them, 120 were mild (49.1%), 16 were moderate (6.56%), and 39 were severe (15.98%). Beta-blocker IIEF score was lower than non-beta-blocker group, ED incidence was higher than non-beta-blocker group, other drug groups such as angiotensin converting enzyme inhibitor group, vascular tone There was no significant difference between the two groups in the group of receptor antagonist, calcium antagonist and diuretic. Conclusion The incidence of ED in hypertensive patients is higher (175 / 244,71.72%). The taking of β-blockers has an adverse effect on the erectile function of patients, while other drugs have similar effects on erectile function.