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目的探讨早期开塞露联合腹部按摩治疗极低出生体质量儿的临床疗效及安全性。方法选取福建医科大学附属泉州第一医院2013年10月—2016年10月收治的极低出生体质量儿78例,按照随机数字表法分为对照组(n=39)和观察组(n=39)。对照组患儿采用常规治疗及腹部按摩,观察组患儿在对照组基础上给予开塞露通便治疗。记录比较两组患儿的喂养不耐受情况(呕吐、腹泻、胃潴留)及新生儿坏死性小肠结肠炎(NEC)发生情况及胎粪排出时间、恢复正常体质量时间及达全肠道喂养时间。结果观察组患儿呕吐、腹胀、胃潴留发生率低于对照组(P<0.05),两组患儿NEC发生率比较,差异无统计学意义(P>0.05)。观察组患儿胎粪排出时间、恢复正常体质量时间及达全肠道喂养时间短于对照组(P<0.05)。结论开塞露联合腹部按摩治疗极低出生体质量儿的效果明显,可有效减少患儿喂养不耐受情况,快速恢复正常体质量,缩短达全胃肠喂养时间,且安全性好。
Objective To investigate the clinical efficacy and safety of early Kaiser dew combined with abdominal massage in the treatment of very low birth weight infants. Methods 78 cases of very low birth weight children admitted to Quanzhou First Hospital of Fujian Medical University from October 2013 to October 2016 were randomly divided into control group (n = 39) and observation group (n = 39). The control group of children with conventional treatment and abdominal massage, the observation group of children in the control group on the basis of Kai Ka Lu laxative treatment. Record the incidence of feeding intolerance (vomiting, diarrhea, gastric retention), neonatal necrotizing enterocolitis (NEC) and meconium discharge time, normal body weight and total gut feeding in two groups time. Results The incidence of vomiting, abdominal distension and gastric retention in the observation group was lower than that of the control group (P <0.05). There was no significant difference in the incidence of NEC between the two groups (P> 0.05). The observation group of children with meconium discharge time, return to normal body mass time and reach the total intestine feeding time is shorter than the control group (P <0.05). Conclusions Kaixialu combined with abdominal massage treatment of very low birth weight children effect is obvious, can effectively reduce the child intolerance, rapid recovery of normal weight, shorten the total gastrointestinal feeding time, and good safety.