过敏性的组胺释放需要钙。根据大鼠腹腔肥大细胞所作实验提出,抗原抗体交互作用很快地打开特异的“钙闸门”,亦即暂时提高了钙离子透过肥大细胞质膜的通透性,钙离子再转而触发释放组胺的过程。作者特就豚鼠作实验,检查过敏时豚鼠肥大细胞释放组胺是否依赖于钙,是否符合钙闸门学说。给雄性豚鼠腹腔内注射3ml含12.5mg的卵 Allergic histamine release requires calcium. According to experiments performed in rat peritoneal mast cells, the antigen-antibody interaction quickly opens up a specific “calcium gate”, that is, temporarily increases the permeability of calcium ions through the plasma membrane of mast cells, which in turn triggers the release group Amine process. The author special experiments on guinea pigs, guinea pigs allergic to check whether histamine release depends on calcium, whether in line with the calcium gate theory. Male guinea pigs were injected intraperitoneally with 3 ml of egg containing 12.5 mg