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目的研究大火草根的化学成分。方法采用硅胶、Sephadex LH-20柱色谱和薄层色谱等方法对甘肃产的大火草根的化学成分进行分离提纯,运用波谱分析技术和理化性质对照等方法进行结构鉴定。结果分离得到8个非生物碱类化合物,分别鉴定为4,5-二甲氧基-7-甲基香豆素(1)、4,7-二甲氧基-5-甲基香豆素(2)、白桦脂酸(3)、齐墩果酸(4)、齐墩果酸3-O-α-L-吡喃阿拉伯糖苷(5)、齐墩果酸3-O-β-D-吡喃半乳糖基-(1→3)-β-D-吡喃葡萄糖苷(6)、常青藤皂苷元3-O-α-L-吡喃阿拉伯糖苷(7)和18-羟基乌索酸(8)。结论除化合物1、2和4外,其余5个化合物均为首次从该植物中分离得到,其中化合物6～8为首次从五加属植物中分离得到。
Objective To study the chemical composition of fire grass roots. Methods Silica gel, Sephadex LH-20 column chromatography and thin layer chromatography were used to separate and purify the chemical constituents from the fire roots of Gansu Province. The chemical constituents were identified by spectral analysis and physical and chemical properties. Results Eight non-alkaloids were isolated and identified as 4,5-dimethoxy-7-methylcoumarin (1), 4,7-dimethoxy-5-methylcoumarin (2), betulinic acid (3), oleanolic acid (4), oleanolic acid 3-O-α-L-arabinopyranoside (5), oleanolic acid 3-O-β-D -galactopyranosyl- (1 → 3) -β-D-glucopyranoside (6), ivy saponin 3-O-α-L-arabinopyranoside (7) and 18- (8). CONCLUSION Compounds 5, 6 and 8 were isolated from plants for the first time except for compounds 1, 2 and 4, of which compounds 6 to 8 were isolated from Caenorhabditis for the first time.