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①目的探讨尿毒症病人心肌受损程度及其意义。②方法对１２例尿毒症病人进行放射性核素９９ｍ锝－甲氧基异丁基异晴（９９ｍＴｃ－ＭＩＢＩ）心肌断层显像检查。③结果１２例病人均显示广泛性、多节段心肌损害，呈花斑样表现，并伴有局限性心肌肥厚。有１１例病人显示左心室扩大，测量左心室腔上下径及左右径分别为５．１０±０．４３ｃｍ和４．２３±０．５９ｃｍ，与正常人左心室腔测量值（上下径３．３６±０．４４ｃｍ，左右径３．０６±０．２６ｃｍ）比较，差异有极显著性（ｔ＝９．１６，５．６８，Ｐ均＜０．０１）。④结论９９ｍＴｃ－ＭＩＢＩ心肌灌注断层显像，能够较确切的评价尿毒症病人的心肌受损程度和位置，观察心室腔的大小。
Objective To investigate the extent of myocardial damage in uremic patients and its significance. Methods 12 cases of uremic patients radionuclide 99m technetium - methoxyisobutyl isosteine (99mTc-MIBI) myocardial tomography examination. ③ Results All 12 patients showed extensive, multi-segmental myocardial damage, showing the appearance of a pattern of flowers with limited myocardial hypertrophy. Eleven patients showed left ventricular enlargement, measurement of left and right ventricular diameter and left and right diameter were 5.10 ± 0.43cm and 4.23 ± 0.59cm, respectively, and normal left ventricular measurements (upper and lower diameter 3.36 ± 0.44cm, left and right diameter 3.06 ± 0.26cm), the difference was significant (t = 9.16,5.68, P <0.01). ④ Conclusion 99mTc-MIBI myocardial perfusion tomography, can more accurately evaluate the extent and location of myocardial damage uremic patients to observe the size of the ventricular cavity.