分别从人胎肝、正常成人肝、肝癌及鼠肝分离得到金属硫蛋白两个亚型（MT－1，MT－2），研究发现鼠肝MT含量最高1．1～1.45mg／克肝重，其次人胎肝1．0～1．3mg／克肝重，正常成人肝MT为1．13mg／克肝重，而肝癌含量最低56μg／克肝重。氨基酸成份分析表明，四种不同来源MT分子中半胱氨酸约占1／3，未发现有芳香族氨基酸。人胎肝MT的抗血清与其他三科来源MT均有交叉反应。并对金属结合能力进行测定。 Two subtypes of metallothionein (MT-1, MT-2) were isolated from human fetal liver, normal adult liver, liver cancer, and rat liver. The study found that MT content in rat liver was the highest at 1.1 to 1.45 mg/g liver weight. , followed by human fetal liver 1.0 ~ 1.3mg / g liver weight, normal adult liver MT is 1.13mg / g liver weight, and liver cancer content is the lowest 56μg / g liver weight. Analysis of amino acid composition showed that cysteine ​​accounted for about 1/3 of MT molecules from four different sources, and no aromatic amino acids were found. The human fetal hepatic MT antiserum cross-reacted with other three families of MTs. And the metal binding capacity was measured.