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1989年5月至8月,本院皮肤科应用息斯敏治疗40例慢性过敏性疾病患者,38例患者经药物治疗获得不同程度的临床效果,未见任何不良反应,其中2例患者于服用息斯敏后,出现严重嗜睡现象,现报告如下: 例1,陈某,男,37岁,患皮肤划痕症2年余,在皮肤科门诊口服息斯敏片,每次10mg,每日一次;维生素C片,每次200mg,每日三次。患者首次服用息斯敏约10min后,便出现嗜睡,持续时间长达26h·停用息斯敏之后,未再发生嗜睡现象。例2,刘某,女,35岁,因患慢性荨麻
From May to August 1989, 40 patients with chronic allergic diseases were treated with astemizole in dermatology department of our hospital. 38 patients were treated with different degrees of clinical efficacy and no adverse reactions were observed. Two of the patients were taking Astemizole, the phenomenon of severe drowsiness, are as follows: Example 1, Chen, male, 37 years old, suffering from skin scarring more than 2 years, in oral dermatology astemizole tablets, each 10mg, daily Once; Vitamin C tablets, 200mg each time, three times daily. After first taking astemizole for about 10 minutes, the patient developed lethargy for up to 26 hours. No lethargy occurred after the drug was stopped. Example 2, Ryu, female, 35 years old, suffering from chronic nettle