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目的:观察健脾活血法联合西药对稳定型心绞痛气虚血瘀证患者中医证候的影响。方法:将240例合格受试者采取中央随机化方法分至试验组(120例)与对照组(120例),应用盲法、安慰剂对照,试验组给予具有健脾活血功效的中药颗粒剂与西药治疗,对照组予安慰剂与西药治疗,西药治疗参考中华医学会心血管病学分会2007年公布的《慢性稳定型心绞痛诊断与治疗指南》,疗程8周,观察中医证候计分在不同时间序列的变化。结果:治疗后,中医证候计分的疾病维度、证候维度、总分试验组较对照组有所改善,差异具有统计学意义(P<0.05)。结论:健脾活血法联合西药治疗能够改善冠心病稳定型心绞痛气虚血瘀证患者的中医证候。
Objective: To observe the effect of invigorating the spleen and promoting blood circulation combined with western medicine on the TCM syndrome of patients with stable angina pectoris and qi deficiency and blood stasis syndrome. Methods: 240 eligible subjects were divided into experimental group (120 cases) and control group (120 cases) by central randomization method. Blind and placebo control groups were given. The experimental group was given traditional Chinese medicine granules with spleen and activating blood circulation effect Western medicine treatment, the control group to placebo and Western medicine treatment, western medicine refer to the Chinese Medical Association Cardiovascular Branch 2007 published “chronic stable angina pectoris diagnosis and treatment guidelines”, the course of treatment for 8 weeks, observed TCM syndrome score Changes in different time series. Results: After treatment, disease score, syndrome dimension and total score of TCM syndrome score improved compared with control group, the difference was statistically significant (P <0.05). Conclusion: The therapy of invigorating the spleen and promoting blood circulation combined with western medicine can improve the TCM syndrome of patients with stable angina pectoris and qi deficiency and blood stasis syndrome of coronary heart disease.