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目的探讨克罗恩病(CD)的临床特点。方法回顾性分析北京市怀柔区第一医院5年来确诊的CD住院病人30例。结果 30例CD中,男多于女(1.31:1),各年龄段均有发病。腹痛(70%)、腹泻(63.3%)为本组患者最常见的胃肠道症状。CD病变范围分型为小肠型8例(27%)、结肠型10例(33%)、回结肠型11例(37%)、其他(口腔、食道)1例(3%)。CD并发症较多,主要为肠梗阻、瘘管及穿孔。7例(23%)CD病人是经手术确诊为CD,其中3例(10%)初诊为“阑尾炎”。结论本院近5年来CD发病数明显增多,CD好发于回盲部,临床表现多样,且缺乏特异性,易延误诊断。
Objective To investigate the clinical features of Crohn’s disease (CD). Methods Retrospective analysis of the first hospital in Huairou District, Beijing, 5 cases of CD inpatients confirmed in 30 cases. Results 30 cases of CD, more men than women (1.31: 1), all age groups have the disease. Abdominal pain (70%) and diarrhea (63.3%) are the most common gastrointestinal symptoms in this group. CD lesions ranged from 8 (27%) for small intestine, 10 (33%) for colon, 11 (37%) for colon-type back and 1 (3%) for other (oral and esophageal) lesions. More CD complications, mainly intestinal obstruction, fistula and perforation. Seven patients (23%) with CD were surgically diagnosed as CD, and 3 (10%) were newly diagnosed as appendicitis. Conclusions Our hospital has obviously increased the incidence of CD in the past 5 years. CD occurs in the ileocecal region. The clinical manifestations are diverse, and it lacks specificity and is easy to delay diagnosis.