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ｒｕｇｇｅｎ等［１］首先在恶性黑色素瘤中发现ＭＡＧＥ１基因，它在胃癌、食管癌等多种恶性肿瘤中都有较高程度的表达，而在正常组织中（除睾丸外）均不表达［２４］。ＭＡＧＥ１基因编码抗原ＭＺ２Ｅ可以被主要组织相容性抗原ＨＬＡＩ类分子提呈，活化并诱导...
Ruggen et al. [1] first discovered the MAGE1 gene in malignant melanoma, which has a high degree of expression in many malignant tumors such as gastric cancer and esophageal cancer, but not in normal tissues (except testis). [2-4]. MAGE-2 gene encoding antigen MZ2-E can be presented by major histocompatibility antigen HLA class I molecules, activated and induced ...