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目的:分析幽门螺杆菌(Helicobacter Pylori,Hp)在青海高原地区回、藏、汉三个民族的感染状况以及与胃癌及各种胃炎性病变之间的关系分析。方法:分析我院连续10年内回、藏、汉三个民族被病理证实为胃癌及炎性病变的病理组织检查结果及Hp的感染状况。结果:Hp总阳性率为49.2%;回族54.8%,藏族49.8%,汉族44.5%,三者之间比较有非常显著性差异。各种炎性病变与胃癌之间的Hp阳性率比较有非常显著性差异。结论:Hp感染与民族、经济文化、饮食卫生等综合因素密切相关。Hp是慢性胃炎的重要致病因素,它与慢性炎症的程度以及肠化生和不典型增生等癌前病变的发生密切相关。
OBJECTIVE: To analyze the prevalence of Helicobacter Pylori (Hp) infection in the areas of Hui, Tibet and Han nationality in Qinghai Plateau and its relationship with gastric cancer and various gastritis lesions. Methods: The histopathological examination results and Hp infection status of gastric cancer and inflammatory lesions confirmed by pathology in our hospital for 10 years were analyzed. Results: The positive rate of Hp was 49.2%, 54.8% for Hui, 49.8% for Tibetan and 44.5% for Han. There were significant differences among the three groups. There is a very significant difference in the positive rate of Hp between various inflammatory lesions and gastric cancer. Conclusion: Hp infection is closely related to the comprehensive factors such as nationality, economy and culture, food hygiene and so on. Hp is an important causative agent of chronic gastritis. It is closely related to the degree of chronic inflammation and the occurrence of precancerous lesions such as intestinal metaplasia and dysplasia.