The coastal ecosystem health assessment is a field of increasing importance. In this paper, a preliminary assessment of ecosystem health in Zhejiang coastal water zone was made, mainly based on remote sensing data and GIS technique. Its spatial and quantitative evaluation was facilitated by the progress of remote sensing and GIS technique development. Firstly, human activities, hydrology and ecosystem problems in the study area were discussed and analyzed. Secondly, from 4 aspects of human stress, physical, chemical and biological responses to anthropogenic activities and natural stress, several indicators such as water transparency (Secchi Disk Depth, SDD), suspended substance concentration, dissolved inorganic nitrogen, active phosphate, chlorophyll, harmful algae bloom, as well as distribution of sewage, sea lanes and port were employed. Thirdly, the Analytic Hierarchical Process was used for indicator weight calculation, and the ecosystem health criteria were established according to the integrative analysis of national water quality criteria, similar coastal ecosystem health research in other places or data inherent properties. The results indicated that from 2005 to 2007 the coastal water ecosystem health value in Zhejiang Province was unhealthy and needs ecological restoration by human intervention.