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分析了牛奶摄入和遗传背景对 1型糖尿病遗传高危婴儿对胰岛素的免疫反应的影响。设计与方法 选择一级亲属为 1型糖尿病 ,且有增加 1型糖尿病发病风险的人类白细胞抗原(HLA)基因型的婴儿 ,母乳喂养 6~ 8个月 ,期间添加配方饮食。随机分为 3组 :以牛奶为基础的配方饮食组 (
The effects of milk intake and genetic background on the immune response to insulin in high-risk infants with type 1 diabetes were analyzed. DESIGN AND METHODS Infants of first-degree relatives of type 1 diabetes and HLA-genotype who are at increased risk for developing type 1 diabetes were breast-fed for 6-8 months while formulating a diet. Randomly divided into 3 groups: milk-based formula diet group (