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为探讨柯萨奇病毒（Ｂ组）所致肺炎的患病率、临床特点及干扰素治疗疗效，于１９９５年１月至１９９６年６月在呼吸科住院的１２１１例肺炎患儿中，随机检测ＣＶＢ抗体８４３例，其中１６３例ＩｇＭ抗体阳性，阳性率１９．３４％。与Ａｄｖ、Ｒｓｖ肺炎比较，ＣＶＢ肺炎的特点为住院前病程长，中毒症状轻，多干咳、少痰、呼吸急促者少见，住院时间较长，伴疱疹性咽峡炎和肌痛，偶有腹泻和皮疹，实验室检查以乳酸脱氢酶及其同功酶异常最显著。随访两个月Ｘ线仍异常，异常率为３５．２９％，提示病程迁延。干扰素治疗组在入院后热程、咳嗽消失时间、住院天数、肺部罗音吸收和胸部Ｘ线炎症吸收时间等方面比对照组有明显缩短，前三项有显著差异（Ｐ＜０．０５），后两项其差异非常显著（Ｐ＜０．０１）。
To investigate the prevalence of pneumonia, clinical features and therapeutic efficacy of interferon induced by Coxsackievirus B (group B), from January 1995 to June 1996, 1211 pneumonia patients admitted to Department of Respiratory Diseases were randomized 843 cases of CVB antibody, of which 163 cases of IgM antibody positive, the positive rate of 19.34%. Compared with Adv, Rsv pneumonia, CVB pneumonia is characterized by long duration of hospitalization, mild symptoms of poisoning, more dry cough, less sputum, rare respiratory shortness, longer hospital stay, herpes angina and myalgia with occasional diarrhea And rash, laboratory tests with lactate dehydrogenase and its isozyme abnormalities most significant. Two months follow-up X-ray is still abnormal, the abnormal rate was 35.29%, suggesting that duration of the disease. Interferon treatment group was significantly shorter than the control group in terms of fever, cough disappearance time, days of hospitalization, pulmonary rales absorption and chest X ray inflammation absorption time, the first three were significantly different (P <0.05 ), The latter two differences were significant (P <0.01).